Break Free, Stay Free

Next-generation solutions for nicotine dependency.

The first once-daily oral medication and advanced medical device for smoking cessation.

Oral Once-Daily Smoking Cessation SPX-0152​

Clinical Trials: 2026

Electronic Delivery of Inhaled Therapeutics (EDIT) Platform​

NIH SBIR Phase I

Smoking accounts for 1 in 5 deaths per year.

In the U.S., 28.3 million Americans smoke cigarettes, 49.2 million people use tobacco products, and vaping is projected to grow 20% each year.

Smoking is the leading cause of preventible death, and in 2018 was estimated by the CDC to cost the U.S. $600 billion.

Yet there has not been a sustainable FDA-approved therapy in over 19 years.

Our Approach

At SpaceRx, we’re tackling the two biggest obstacles to quitting smoking: underperforming medications and deeply ingrained habits.

Most treatments fall short because they fail to address both the physical and psychological sides of addiction.

We’re developing next-generation pharmaceuticals that work with the body to disrupt nicotine dependence at its core, to make quitting not just possible—but sustainable.

News & Events

June 16 - 19, 2025

BIO International Convention

Boston Convention & Exhibition Center

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Related Topics

“Smoking cessation pill may help youth quit vaping”

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Summer, 2025

I-CORP at NIH

For SBIR/STTR startups commercializing biomedical innovations.

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Related Topics

Smoking Cessation And Nicotine De-Addiction Market Impact of AI and Automation

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Supported By

We’re proud to have the continued support of NIH NIDA through multiple SBIR/STTR awards, which are helping drive both projects toward meaningful, real-world impact.